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Cimlanod
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    Cimlanod

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    Cimlanod
    Cimlanod.svg
    Legal status
    Legal status
    • Investigational
    Identifiers
    • N-Hydroxy-5-methylfuran-2-sulfonamide
    CAS Number
    PubChem CID
    DrugBank
    UNII
    Chemical and physical data
    Formula C5H7NO4S
    Molar mass 177.17 g·mol−1
    3D model (JSmol)
    • CC1=CC=C(O1)S(=O)(=O)NO

    Cimlanod (development codes CXL-1427 and BMS-986231) is an experimental drug for the treatment of acute decompensated heart failure. It was discovered by Cardioxyl Pharmaceuticals, which was acquired by Bristol-Myers Squibb. It is a nitroxyl donor.

    Cimlanod is a prodrug of CXL-1020.

    A preliminary study showed efficacy in patients with class III and IV heart failure. A phase II clinical trial was completed in 2016.


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