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Antibiotic
Clofoctol
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Clofoctol

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Clofoctol
Structural formula of clofoctol
Ball-and-stick model of the clofoctol molecule
Clinical data
AHFS/Drugs.com International Drug Names
Routes of
administration		 Rectal (suppository)
ATC code
Pharmacokinetic data
Bioavailability 98%
Metabolism Hepatic glucuronidation
Excretion Biliary
Identifiers
  • 2-[(2,4-dichlorophenyl)methyl]-
    4-(2,4,4-trimethylpentan-2-yl)phenol
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.048.739
Chemical and physical data
Formula C21H26Cl2O
Molar mass 365.34 g·mol−1
3D model (JSmol)
  • Clc1cc(Cl)ccc1Cc2cc(ccc2O)C(C)(C)CC(C)(C)C
  • InChI=1S/C21H26Cl2O/c1-20(2,3)13-21(4,5)16-7-9-19(24)15(11-16)10-14-6-8-17(22)12-18(14)23/h6-9,11-12,24H,10,13H2,1-5H3 checkY
  • Key:HQVZOORKDNCGCK-UHFFFAOYSA-N checkY
  (verify)

Clofoctol is a bacteriostatic antibiotic. It is used in the treatment of respiratory tract and ear, nose and throat infections caused by Gram-positive bacteria. It has been marketed in France till 2005 under the trade name Octofene and in Italy as Gramplus.

It is only functional against Gram-positive bacteria.

It penetrates into human lung tissue.

Apteeus is developing clofoctol as a potential therapy against SARS-CoV-2.



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