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Adrenergic release inhibitors
Debrisoquine
Другие языки:

Debrisoquine

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Debrisoquine
Debrisoquine.svg
Names
Preferred IUPAC name
3,4-Dihydroisoquinoline-2(1H)-carboximidamide
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
DrugBank
ECHA InfoCard 100.013.155
KEGG
MeSH Debrisoquine
PubChem CID
UNII
  • InChI=1S/C10H13N3/c11-10(12)13-6-5-8-3-1-2-4-9(8)7-13/h1-4H,5-7H2,(H3,11,12) checkY
    Key: JWPGJSVJDAJRLW-UHFFFAOYSA-N checkY
  • InChI=1/C10H13N3/c11-10(12)13-6-5-8-3-1-2-4-9(8)7-13/h1-4H,5-7H2,(H3,11,12)
    Key: JWPGJSVJDAJRLW-UHFFFAOYAE
  • [N@H]=C(N)N2Cc1c(cccc1)CC2
Properties
C10H13N3
Molar mass 175.23032
Pharmacology
C02CC04 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY verify (what is checkY☒N ?)

Debrisoquine is a derivative of guanidine. It is an antihypertensive drug similar to guanethidine. Debrisoquine is frequently used for phenotyping the CYP2D6 enzyme, a drug-metabolizing enzyme.

See also

The guanidine part of the molecule also appears in guanoxan and guanadrel.

  • The 7-bromo analog of Debrisoquine is called Guanisoquin.



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