Dolutegravir/rilpivirine
| Combination of | |
|---|---|
| Dolutegravir | HIV integrase strand transfer inhibitor (INSTI) |
| Rilpivirine | HIV non-nucleoside reverse-transcriptase inhibitor (NNRTI) |
| Clinical data | |
| Trade names | Juluca |
| AHFS/Drugs.com | Monograph |
| License data | |
| Pregnancy category |
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| Routes of administration |
By mouth |
| ATC code | |
| Legal status | |
| Legal status | |
| Identifiers | |
| KEGG | |
Dolutegravir/rilpivirine, sold under the brand name Juluca, is a fixed-dose combination antiretroviral medication for the treatment of HIV/AIDS. It contains the medicines dolutegravir and rilpivirine. It is taken by mouth.
The most common adverse reactions (of all severity grades) are diarrhea and headache.
Dolutegravir/rilpivirine was approved for use in the United States in November 2017, and for use in the European Union in May 2018.
Medical uses
Dolutegravir/rilpivirine is indicated for the treatment of human immunodeficiency virus type 1 (HIV-1) infection in adults who are virologically-suppressed (HIV-1 RNA <50 copies/mL) on a stable antiretroviral regimen for at least six months with no history of virological failure and no known or suspected resistance to any non-nucleoside reverse transcriptase inhibitor or integrase inhibitor.
External links
- "Dolutegravir mixture with rilpivirine". Drug Information Portal. U.S. National Library of Medicine.