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Combination vaccines
DTaP-IPV/Hib vaccine
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    DTaP-IPV/Hib vaccine

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    DTaP-IPV/Hib vaccine
    Combination of
    DTaP vaccine Vaccine
    Inactivated poliovirus vaccine Vaccine
    Hib vaccine Vaccine
    Clinical data
    Trade names Pentacel, Pediacel, Infanrix IPV + Hib, others
    AHFS/Drugs.com FDA Professional Drug Information
    Routes of
    administration    		 Intramuscular injection
    ATC code
    Legal status
    Legal status
    Identifiers
    CAS Number

    DTaP-IPV/Hib vaccine is a 5-in-1 combination vaccine that protects against diphtheria, tetanus, whooping cough, polio, and Haemophilus influenzae type B.

    Its generic name is 'diphtheria and tetanus toxoids and acellular pertussis adsorbed, inactivated poliovirus and haemophilus B conjugate vaccine', and it is also known as DTaP-IPV-Hib.

    Uses

    DTaP-IPV/Hib vaccine is administered to young children to immunise against diphtheria, tetanus, pertussis, poliomyelitis, and diseases caused by Haemophilus influenzae type B.

    Formulations

    A branded formulation marketed in the United States is Pentacel, manufactured by Sanofi Pasteur.

    Pentacel is known in the UK and Canada as Pediacel.

    An equivalent vaccine marketed in the UK and Canada by GlaxoSmithKline is Infanrix IPV + Hib. This is a two-part vaccine. The DTaP-IPV component is supplied as a sterile liquid, which is used to reconstitute lyophilized (freeze-dried) Hib vaccine.

    Pentaxim is a liquid formulation marketed by Sanofi Pasteur.

    Availability

    It is only licensed for young children. In the US the FDA have approved the vaccine for children from age 6 weeks up to age 5 years. It was used in the UK until 2017, following which a 6-in-1 vaccine became available containing the additional protection against Hepatitis B.



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