Early onset dementia

Early onset dementia is dementia in which symptoms first appear before the age of 65. The term favored until about 2000 was presenile dementia; young onset dementia is also used.

Early onset dementia may be caused by degenerative or vascular disease, or it may be due to other causes, such as alcohol-related dementia and other inflammatory or infectious processes.Early-onset Alzheimer's disease, vascular dementia and frontotemporal lobar degeneration are the most common forms of early onset dementia, with Alzheimer's accounting for between 30 and 40%. Early onset dementia may also occur, less frequently, in the Lewy body dementias (dementia with Lewy bodies and Parkinson's disease dementia), multiple sclerosis, Huntington's disease and other conditions.

Further reading

• Collins JD, Henley SM, Suárez-González A (July 2020). "A systematic review of the prevalence of depression, anxiety, and apathy in frontotemporal dementia, atypical and young-onset Alzheimer's disease, and inherited dementia". Int Psychogeriatr (Review): 1–20. doi:10.1017/S1041610220001118. PMID 32684177. S2CID 220653830.
• Ducharme S, Dols A, Laforce R, et al. (June 2020). "Recommendations to distinguish behavioural variant frontotemporal dementia from psychiatric disorders". Brain (Review). 143 (6): 1632–1650. doi:10.1093/brain/awaa018. PMC 7849953. PMID 32129844.
• Nwadiugwu M (September 2021). "Early-onset dementia: key issues using a relationship-centred care approach". Postgrad Med J (Review). 97 (1151): 598–604. doi:10.1136/postgradmedj-2020-138517. PMC 8408578. PMID 32883770.
• Roman de Mettelinge T, Calders P, Cambier D (2021). "The Effects of Aerobic Exercise in Patients with Early-Onset Dementia: A Scoping Review". Dement Geriatr Cogn Disord (Review). 50 (1): 9–16. doi:10.1159/000516231. PMID 33957623. S2CID 233983643.