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Prodrug
Etofibrate
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Etofibrate

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Etofibrate
Etofibrate.svg
Space-filling model of the etofibrate molecule
Clinical data
AHFS/Drugs.com International Drug Names
ATC code
Pharmacokinetic data
Metabolism Hydrolyzed to clofibric acid and niacin
Identifiers
  • 2-[(pyridin-3-yl)carbonyloxy]ethyl 2-(4-chlorophenoxy)-2-methylpropanoate
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.046.115
Chemical and physical data
Formula C18H18ClNO5
Molar mass 363.79 g·mol−1
3D model (JSmol)
  • O=C(OCCOC(=O)C(Oc1ccc(Cl)cc1)(C)C)c2cccnc2
  • InChI=1S/C18H18ClNO5/c1-18(2,25-15-7-5-14(19)6-8-15)17(22)24-11-10-23-16(21)13-4-3-9-20-12-13/h3-9,12H,10-11H2,1-2H3 checkY
  • Key:XXRVYAFBUDSLJX-UHFFFAOYSA-N checkY
  (verify)

Etofibrate is a fibrate. It is a combination of clofibrate and niacin, linked together by an ester bond. In the body, clofibrate and niacin separate and are released gradually, in a manner similar to controlled-release formulations.



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