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Abandoned drugs
Fenmetozole
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    Fenmetozole

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    Fenmetozole
    Fenmetozole.png
    Clinical data
    ATC code
    • None
    Identifiers
    • 2-[(3,4-dichlorophenoxy)methyl]-4,5-dihydro-1H-imidazole
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C10H10Cl2N2O
    Molar mass 245.10 g·mol−1
    3D model (JSmol)
    • Clc2ccc(OCC/1=N/CCN\1)cc2Cl

    Fenmetozole (DH-524) is a drug which was patented as an antidepressant, but was later studied as an antagonist of the effects of ethanol, though results were poor and it even increased its effects in some cases. It acts as an α2-adrenergic receptor antagonist similarly to other imidazoles like idazoxan. It was never marketed.

    Fenoxazoline has the precise same formula, albeit instead of the 3',4'-dich, an ortho-isopropyl group was chosen instead.


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