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Respiratory system drug stubs
Fenspiride
Другие языки:

Fenspiride

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Fenspiride
Fenspiride.svg
Fenspiride ball-and-stick model.png
Clinical data
Trade names Eurespal, Pneumorel
AHFS/Drugs.com International Drug Names
Routes of
administration		 Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
Bioavailability 90%
Elimination half-life 14–16 hours
Excretion Urine (90%), feces (~10%)
Identifiers
  • 8-(2-phenylethyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard 100.023.411
Chemical and physical data
Formula C15H20N2O2
Molar mass 260.337 g·mol−1
3D model (JSmol)
  • c1ccc(cc1)CCN2CCC3(CC2)CN=C(O3)O
  • InChI=1S/C15H20N2O2/c18-14-16-12-15(19-14)7-10-17(11-8-15)9-6-13-4-2-1-3-5-13/h1-5H,6-12H2,(H,16,18) ☒N
  • Key:FVNFBBAOMBJTST-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Fenspiride (INN, brand names Eurespal, Pneumorel and others) is an oxazolidinone spiro compound used as a drug in the treatment of certain respiratory diseases. The pharmacotherapeutic classification is antitussives. In Russia it was approved for the treatment of acute and chronic inflammatory diseases of ENT organs (ear, nose, throat) and the respiratory tract (like rhinopharyngitis, laryngitis, tracheobronchitis, otitis and sinusitis), as well as for maintenance treatment of asthma.Russia, Romania, France and other European countries withdrew fenspiride-based drugs from the market due to the risk of QT prolongation and torsades de pointes. Fenspiride is known to have activity as an alpha-1 blocker.



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