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Ferroquine
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Ferroquine

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Ferroquine
Ferroquine.png
Identifiers
  • 7-chloro-N-(2-((dimethylamino)methyl)ferrocenyl)quinolin-4-amine
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard 100.208.008
Chemical and physical data
Formula C23H24ClFeN3
Molar mass 433.76 g·mol−1
  • InChI=1S/C18H19ClN3.C5H5.Fe/c1-22(2)12-14-5-3-4-13(14)11-21-17-8-9-20-18-10-15(19)6-7-16(17)18;1-2-4-5-3-1;/h3-10H,11-12H2,1-2H3,(H,20,21);1-5H;/q2*-1;+2
  • Key:DDENDDKMBDTHAX-UHFFFAOYSA-N

Ferroquine is a synthetic compound related to chloroquine which acts as an antimalarial, and shows good activity against chloroquine-resistant strains. It contains an organometallic ferrocene ring which is unusual in pharmaceuticals, and while it was first reported in 1997, it has progressed slowly through clinical trials, with results from Phase II trials showing reasonable safety and efficacy, and further trials ongoing.


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