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Antineoplastic and immunomodulating drugs
Gardiquimod
Другие языки:

Gardiquimod

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Gardiquimod
Gardiquimod.svg
Identifiers
  • 1-(4-Amino-2-((ethylamino)methyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
ECHA InfoCard 100.233.311
Chemical and physical data
Formula C17H23N5O
Molar mass 313.405 g·mol−1
3D model (JSmol)
  • CCNCc1nc2c(n1CC(C)(C)O)c3ccccc3nc2N
  • InChI=1S/C17H23N5O/c1-4-19-9-13-21-14-15(22(13)10-17(2,3)23)11-7-5-6-8-12(11)20-16(14)18/h5-8,19,23H,4,9-10H2,1-3H3,(H2,18,20)
  • Key:FHJATBIERQTCTN-UHFFFAOYSA-N
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Gardiquimod is an experimental drug which acts selectively at both mouse and human forms of toll-like receptor 7 (TLR7). It functions as an immune response modifier. The core structure is 1H-imidazo[4,5-c]quinoline, as found in related drugs such as imiquimod and resiquimod. It is structurally very similar to resiquimod differing only by an oxygen for nitrogen switch.


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