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Gedunin
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IUPAC name
Gedunin
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Systematic IUPAC name
[(1S,2R,4S,7S,8S,11R,12R,17R,19R)-7-(furan-3-yl)-1,8,12,16,16-pentamethyl-5,15-dioxo-3,6-dioxapentacyclo[9.8.0.02,4.02,8.012,17]nonadec-13-en-19-yl] acetate | |
Other names
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Gedunin is a pentacyclic triterpenoid with the molecular formula C28H43O7. It is most notably found in Azadirachta indica, but is a constituent of several other plants. Gedunin shows therapeutic potential in the treatment of leukemia, and Parkinson's disease.
Natural occurrence
Azadirachta indica is the most notable source of gedunin, but it has also been found in the following plants:
- Cedrela fissilis
- Cedrela odorata
- Cedrela salvadorensis
- Entandrophragma angolense
- Khaya grandifoliola
- Melia azedarach
- Toona sinensis
- Xylocarpus granatum