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GSK-4112
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    GSK-4112

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    GSK-4112
    GSK-4112 Structure.svg
    Identifiers
    • tert-butyl 2-[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]acetate
    CAS Number
    PubChem CID
    ChemSpider
    ChEMBL
    Chemical and physical data
    Formula C18H21ClN2O4S
    Molar mass 396.89 g·mol−1
    3D model (JSmol)
    • CC(C)(C)OC(=O)CN(CC1=CC=C(C=C1)Cl)CC2=CC=C(S2)[N+](=O)[O-]
    • InChI=1S/C18H21ClN2O4S/c1-18(2,3)25-17(22)12-20(10-13-4-6-14(19)7-5-13)11-15-8-9-16(26-15)21(23)24/h4-9H,10-12H2,1-3H3
    • Key:WYSLOKHVFKLWOU-UHFFFAOYSA-N

    GSK-4112 is an experimental drug that was developed by GlaxoSmithKline as an agonist of Rev-ErbAα. It is used for studying regulation of the circadian rhythm and its influence on diverse processes such as adipogenesis, regulation of bone density, and inflammation.

    See also



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