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Abandoned drugs
Guanoclor
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Guanoclor

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Guanoclor
Guanoclor.png
Clinical data
ATC code
Identifiers
  • 2-{[2-(2,6-Dichlorophenoxy)ethyl]amino}guanidine
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard 100.023.334
Chemical and physical data
Formula C9H12Cl2N4O
Molar mass 263.12 g·mol−1
3D model (JSmol)
  • C1=CC(=C(C(=C1)Cl)OCCNNC(=N)N)Cl
  • InChI=1S/C9H12Cl2N4O/c10-6-2-1-3-7(11)8(6)16-5-4-14-15-9(12)13/h1-3,14H,4-5H2,(H4,12,13,15)
  • Key:XIHXRRMCNSMUET-UHFFFAOYSA-N
  (verify)

Guanoclor (INN), also known as guanochlor, is a sympatholytic drug. It is known to bind to non-adrenergic sites in pig kidney membranes.

Synthesis

When β-(2,6-dichlorophenoxy)ethyl bromide (1) is reacted with hydrazine to give 2, and this is reacted with S-methylthiourea, guanochlor (3) results.

Guanoclor synthesis

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