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Haplogroup JT (mtDNA)
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Haplogroup JT (mtDNA)

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Haplogroup JT
Possible time of origin 50,300 YBP
Possible place of origin Southwest Asia
Ancestor R2'JT
Descendants J, T
Defining mutations 11251, 15452A, 16126

Haplogroup JT is a human mitochondrial DNA (mtDNA) haplogroup.

Origin

Haplogroup JT is descended from the macro-haplogroup R. It is the ancestral clade to the mitochondrial haplogroups J and T.

JT (predominantly J) was found among the ancient Etruscans. The haplogroup has also been found among Iberomaurusian specimens dating from the Epipaleolithic at the Taforalt prehistoric site. One ancient individual carried a haplotype, which correlates with either the JT clade or the haplogroup H subclade H14b1 (1/9; 11%).

Subclades

Tree

This phylogenetic tree of haplogroup JT subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation and subsequent published research.

  • R2'JT

Health

Maternally inherited ancient mtDNA variants have clear impact on the presentation of disease in a modern society. Superhaplogroup JT is an example of reduced risk of Parkinson's disease And mitochondrial and mtDNa alterations continue to be promising disease biomarkers.

See also

Phylogenetic tree of human mitochondrial DNA (mtDNA) haplogroups

  Mitochondrial Eve (L)    
L0 L1–6  
L1 L2   L3     L4 L5 L6
M N  
CZ D E G Q   O A S R   I W X Y
C Z B F R0   pre-JT   P   U
HV JT K
H V J T

External links



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