Heiko Enderling is a German-American mathematical biologist and mathematical oncologist whose research topics include radiotherapy, tumor-immune interactions, cancer stem cells, and dynamic biomarkers. He is a Senior Member in the Department of Integrated Mathematical Oncology at Moffitt Cancer Center, editor of the Bulletin of Mathematical Biology, and president of the Society for Mathematical Biology (2021–2023).
Education and career
Enderling graduated from Otto von Guericke University Magdeburg with a degree in Computervisualistik in 2003, and completed his PhD at the University of Dundee in 2006. His dissertation, Mathematical modelling of breast tumour development, treatment and recurrence, was jointly supervised by Mark Chaplain, Glenn Rowe, and Alexander Anderson.
After postdoctoral research at Tufts University, he was an assistant professor at Tufts University from 2010 to 2013 before moving to Moffitt Cancer Center. At Moffitt, he directs a research group on Quantitative Personalized Oncology, with the goal to integrate quantitative modeling into oncology decision making.
He is president of the Society for Mathematical Biology from 2021 to 2023, the major academic society in the field.
Publications
His most cited papers are:
- Enderling, Heiko; Chaplain, Mark A.J.; Anderson, Alexander R.A.; Vaidya, Jayant S. (2007). "A mathematical model of breast cancer development, local treatment and recurrence". Journal of Theoretical Biology. Elsevier BV. 246 (2): 245–259. Bibcode:2007JThBi.246..245E. doi:10.1016/j.jtbi.2006.12.010. ISSN 0022-5193. PMID 17289081.
- Enderling, Heiko; Anderson, Alexander R.A.; Chaplain, Mark A.J.; Beheshti, Afshin; Hlatky, Lynn; Hahnfeldt, Philip (11 November 2009). "Paradoxical Dependencies of Tumor Dormancy and Progression on Basic Cell Kinetics". Cancer Research. American Association for Cancer Research (AACR). 69 (22): 8814–8821. doi:10.1158/0008-5472.can-09-2115. ISSN 0008-5472. PMID 19887613. S2CID 16251292.
- Enderling, Heiko; Chaplain, Mark (31 August 2014). "Mathematical Modeling of Tumor Growth and Treatment". Current Pharmaceutical Design. Bentham Science Publishers Ltd. 20 (30): 4934–4940. doi:10.2174/1381612819666131125150434. hdl:10023/7710. ISSN 1381-6128. PMID 24283955.
Recognition
Enderling was named a Centennial Postdoctoral Fellow of the American Association for Cancer Research in 2008, and Fellow of the Society for Mathematical Biology in 2021.