IgG4-related skin disease

IgG4-related skin disease is the recommended name for skin manifestations in IgG4-related disease (IgG4-RD). Multiple different skin manifestations have been described.

Classification

Although a clear understanding of the various skin lesions in IgG4-related disease is a work in progress, skin lesions have been classified into subtypes based on documented cases:

• Angiolymphoid hyperplasia with eosinophilia (or lesions that mimic it) and cutaneous pseudolymphoma
• Cutaneous plasmacytosis
• Eyelid swelling (as part of Mikulicz's disease)
• Psoriasis-like eruptions
• Unspecified maculopapular or erythematous eruptions
• Hypergammaglobulinemic purpura and urticarial vasculitis
• Impaired blood supply to fingers or toes, leading to Raynaud's phenomenon or gangrene

In addition, Wells syndrome has also been reported in a case of IgG4-related disease.

See also

• IgG4-related disease

Note

Note: