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Antiemetics
Indisetron
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    Indisetron

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    Indisetron
    Indisetron.svg
    Clinical data
    Trade names Sinseron
    Other names N-3389
    ATC code
    • none
    Legal status
    Legal status
    • Rx in Japan
    Identifiers
    • N-[(1R,5S)-3,9-Dimethyl-3,9-diazabicyclo[3.3.1]nonan-7-yl]-1H-indazole-3-carboxamide
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    KEGG
    ChEBI
    ChEMBL
    Chemical and physical data
    Formula C17H23N5O
    Molar mass 313.405 g·mol−1
    3D model (JSmol)
    • CN1C[C@H]2CC(C[C@@H](C1)N2C)NC(=O)C3=NNC4=CC=CC=C43
    • InChI=1S/C17H23N5O/c1-21-9-12-7-11(8-13(10-21)22(12)2)18-17(23)16-14-5-3-4-6-15(14)19-20-16/h3-6,11-13H,7-10H2,1-2H3,(H,18,23)(H,19,20)/t11?,12-,13+
    • Key:MHNNVDILNTUWNS-YHWZYXNKSA-N

    Indisetron (INN; trade name Sinseron) is a drug used for prophylaxis of chemotherapy-induced nausea and vomiting. It was approved by Japan's Pharmaceuticals and Medical Devices Agency in 2004.

    Indisetron exerts its effects as a dual serotonin 5-HT3 and 5-HT4 receptor antagonist.

    See also



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