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Experimental cancer drugs
Indisulam
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    Indisulam

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    Indisulam
    Indisulam.svg
    Names
    Preferred IUPAC name
    N1-(3-Chloro-1H-indol-7-yl)benzene-1,4-disulfonamide
    Other names
    E7070
    Identifiers
    3D model (JSmol)
    ChEBI
    ChEMBL
    ChemSpider
    DrugBank
    KEGG
    PubChem CID
    UNII
    • InChI=1S/C14H12ClN3O4S2/c15-12-8-17-14-11(12)2-1-3-13(14)18-24(21,22)10-6-4-9(5-7-10)23(16,19)20/h1-8,17-18H,(H2,16,19,20)
      Key: SETFNECMODOHTO-UHFFFAOYSA-N
    • C1=CC2=C(C(=C1)NS(=O)(=O)C3=CC=C(C=C3)S(=O)(=O)N)NC=C2Cl
    Properties
    C14H12ClN3O4S2
    Molar mass 385.84 g·mol−1
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    Indisulam is a chloroindolyl sulfonamide cell cycle inhibitor that exhibits antitumor activity in vitro and in an animal model. This compound affects cell cycle progression in human tumor cells and is being studied for the treatment of cancers such as melanomas and blood-borne cancers such as leukemia.


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