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Epidemiology
Institute for Disease Modeling
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    Institute for Disease Modeling

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    Institute for Disease Modeling (IDM) is an institute within the Global Health Division of the Bill and Melinda Gates Foundation. Established in 2008 as part of the Global Good Fund, a non-profit subsidiary of Intellectual Ventures (IV) funded by Bill and Melinda Gates, IDM has transitioned in mid-2020 to the Gates Foundation.

    IDM specializes in mathematical modelling of infectious disease and other quantitative global health research. Its models include malaria, polio, measles, COVID-19 and HIV (with EMOD). IDM releases source code of their stable models to the public. While at IV, the institute was located in Bellevue, Washington. After the outbreak of COVID-19 in Washington State, IDM has transitioned to all-remote work with no physical offices. It will eventually relocate to the Gates Foundation's main office in Seattle.

    Disease modeling software

    EMOD is the group's individual-based disease modeling software (not a compartmental model) initially coded c. 2005. It has been released to the public as open-source software. The software can model malaria, HIV, tuberculosis, measles, dengue, polio and typhoid.

    In 2020, IDM developed a designated COVID-19 agent-based model named "Covasim." It was used initially to advise on decision-making during the COVID-19 pandemic in Oregon and in Washington State, gaining national attention. Covasim, coded in Python, is open-source and has been used by independent researchers around the world.

    Sources

    • Jeffrey W Eaton; Nicolas Bacaër; Anna Bershteyn; Valentina Cambiano; Anne Cori; Rob E Dorrington; et al. (October 2015), "Assessment of epidemic projections using recent HIV survey data in South Africa: a validation analysis of ten mathematical models of HIV epidemiology in the antiretroviral therapy era", The Lancet, 3 (10): e598–e608, doi:10.1016/S2214-109X(15)00080-7, PMID 26385301
    • Bershteyn, Anna; Gerardin, Jaline; Bridenbecker, Daniel; Lorton, Christopher W; Bloedow, Jonathan; Baker, Robert S; Chabot-Couture, Guillaume; Chen, Ye; Fischle, Thomas; Frey, Kurt; Gauld, Jillian S; Hu, Hao; Izzo, Amanda S; Klein, Daniel J; Lukacevic, Dejan; McCarthy, Kevin A; Miller, Joel C; Ouedraogo, Andre Lin; Perkins, T Alex; Steinkraus, Jeffrey; ten Bosch, Quirine A; Ting, Hung-Fu; Titova, Svetlana; Wagner, Bradley G; Welkhoff, Philip A; Wenger, Edward A; Wiswell, Christian N (2018), "Implementation and applications of EMOD, an individual-based multi-disease modeling platform", Pathogens and Disease, 76 (5), doi:10.1093/femspd/fty059, ISSN 2049-632X, PMC 6067119, PMID 29986020

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