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Antiinfective agent stubs
Isometamidium chloride
Другие языки:

Isometamidium chloride

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Isometamidium chloride
Isometamidium chloride.png
Clinical data
ATCvet code
Identifiers
  • 3-[N'-[(3-amino-5-ethyl-6-phenyl-8-phenanthridin-5-iumyl)imino]hydrazino]benzamidine chloride
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard 100.047.191
Chemical and physical data
Formula C28H26ClN7
Molar mass 496.02 g·mol−1
3D model (JSmol)
  • [Cl-].[N@H]=C(N)c1cc(ccc1)N/N=N/c4ccc3c2ccc(N)cc2[n+](c(c3c4)c5ccccc5)CC
  • InChI=1S/C28H25N7.ClH/c1-2-35-26-16-20(29)11-13-24(26)23-14-12-22(17-25(23)27(35)18-7-4-3-5-8-18)33-34-32-21-10-6-9-19(15-21)28(30)31;/h3-17,29H,2H2,1H3,(H4,30,31,32,33);1H
  • Key:QNZJTSGALAVCLH-UHFFFAOYSA-N

Isometamidium chloride is a triazene trypanocidal agent used in veterinary medicine.

It consists of a single Ethidium bromide like subunit linked to a fragment of the diminazene molecule.

Resistance

The Gibe River Valley in southwest Ethiopia showed universal resistance between July 1989 and February 1993. This likely indicates a permanent loss of function in this area against the tested target, T. congolense isolated from Boran cattle.


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