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Experimental drugs
Itruvone
Другие языки:

    Itruvone

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    Itruvone
    Itruvone.svg
    Clinical data
    Other names PH10; PH10A; PH10 NS; Pregn-4-en-20-yn-3-one
    Routes of
    administration    		 Intranasal (spray)
    Identifiers
    • (8S,9S,10R,13S,14S,17R)-17-ethynyl-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    KEGG
    Chemical and physical data
    Formula C21H28O
    Molar mass 296.454 g·mol−1
    3D model (JSmol)
    • C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2C#C)CCC4=CC(=O)CC[C@]34C
    • InChI=1S/C21H28O/c1-4-14-6-8-18-17-7-5-15-13-16(22)9-11-21(15,3)19(17)10-12-20(14,18)2/h1,13-14,17-19H,5-12H2,2-3H3/t14-,17-,18-,19-,20+,21-/m0/s1
    • Key:CHOUAXDNNAVGHR-NWSAAYAGSA-N

    Itruvone (INN; developmental code name PH10), also known as pregn-4-en-20-yn-3-one, is a vomeropherine which is under development by VistaGen Therapeutics as a nasal spray for the treatment of major depressive disorder.

    See also




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