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JNJ-26990990
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    JNJ-26990990

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    JNJ-26990990
    JNJ-26990990.svg
    Clinical data
    Other names N-((Benzo[b]thien-3-yl)methyl)sulfamide
    Identifiers
    • 3-[(Sulfamoylamino)methyl]-1-benzothiophene
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEBI
    ChEMBL
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C9H10N2O2S2
    Molar mass 242.31 g·mol−1
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    JNJ-26990990 is a broad-spectrum anticonvulsant drug currently under development by Janssen Pharmaceutica as a second-generation follow-up to the marketed drug topiramate. It was designed to have the same anticonvulsant effects as topiramate, but without the side effects associated with topiramate's carbonic anhydrase inhibition. It also has potential use in the treatment of inflammatory pain, neuropathic pain, and depression.

    JNJ-26990990 entered phase II clinical trials in October 2007.

    Metabolites and radioactive isotope-labeled derivatives of JNJ-26990990 have also been prepared to support its development.

    See also


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