Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
CB1 receptor agonists
JWH-150
Другие языки:

    JWH-150

    Подписчиков: 0, рейтинг: 0
    JWH-150
    JWH-150.svg
    Legal status
    Legal status
    Identifiers
    • (1-butyl-5-phenylpyrrol-3-yl)-naphthalen-1-ylmethanone  
    CAS Number
    PubChem CID
    ChemSpider
    Chemical and physical data
    Formula C25H23NO
    Molar mass 353.465 g·mol−1
    3D model (JSmol)
    • CCCCN1C=C(C=C1C2=CC=CC=C2)C(=O)C3=CC=CC4=CC=CC=C43
    • InChI=1S/C25H23NO/c1-2-3-16-26-18-21(17-24(26)20-11-5-4-6-12-20)25(27)23-15-9-13-19-10-7-8-14-22(19)23/h4-15,17-18H,2-3,16H2,1H3   checkY
    • Key:PTIAQHRJOQEMCO-UHFFFAOYSA-N  checkY

    JWH-150 ((1-butyl-5-phenylpyrrol-3-yl)-naphthalen-1-ylmethanone) is a synthetic cannabinoid from the naphthoylpyrrole family which acts as an agonist of the CB1 (Ki = 60 ± 1nM) and CB2 (Ki = 15 ± 2nM) receptors, with a moderate (4x) selectivity for the CB2 receptor. JWH-150 was first synthesized in 2006 by John W. Huffman and colleagues to examine the nature of ligand binding to the CB1 receptor.

    Legality

    In the United States JWH-150 is not federally scheduled, although some states have passed legislation banning the sale, possession, and manufacture of JWH-150.

    In Canada, JWH-150 and other naphthoylpyrrole-based cannabinoids are Schedule II controlled substances under the Controlled Drugs and Substances Act.

    In the United Kingdom, JWH-150 and other naphthoylpyrrole-based cannabinoids are considered Class B drugs under the Misuse of Drugs Act 1971.

    See also



    Новое сообщение