JWH-398

JWH-398

Legal status
Legal status	CA: Schedule II DE: NpSG (Industrial and scientific use only) UK: Class B US: Schedule I Illegal in Latvia
Identifiers
IUPAC name 1-Pentyl-3-(4-chloro-1-naphthoyl)indole
CAS Number	1292765-18-4 N
ChemSpider	28647395 N
UNII	RX0E95S90H
CompTox Dashboard (EPA)	DTXSID40156131
Chemical and physical data
Formula	C24H22ClNO
Molar mass	375.90 g·mol−1
3D model (JSmol)	Interactive image
SMILES c14ccccc1n(CCCCC)cc4C(=O)c(cc3)c2ccccc2c3Cl
InChI InChI=1S/C24H22ClNO/c1-2-3-8-15-26-16-21(19-11-6-7-12-23(19)26)24(27)20-13-14-22(25)18-10-5-4-9-17(18)20/h4-7,9-14,16H,2-3,8,15H2,1H3 N Key:IUWBHGFOHXVVKV-UHFFFAOYSA-N N
NY (what is this?)  (verify)

JWH-398 is an analgesic chemical from the naphthoylindole family, which acts as a cannabinoid agonist at both the CB₁ and CB₂ receptors. It has mild selectivity for CB₁ with a K_i of 2.3 nM and 2.8 nM at CB₂. This synthetic chemical compound was identified by the EMCDDA as an ingredient in three separate "herbal incense" products purchased from online shops between February and June 2009. It was discovered by, and named after, John W. Huffman.

In the United States, JWH-398 is a Schedule I controlled substance.

See also

• 5F-JWH-398
• JWH-122
• JWH-424