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Eli Lilly and Company
Kappadione
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    Kappadione

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    Kappadione
    Kappadione.svg
    Clinical data
    Routes of
    administration    		 Injection
    ATC code
    • none
    Legal status
    Legal status
    • US: Rx only, discontinued (was FDA approved)
    • In general: ℞ (Prescription only)
    Identifiers
    • Tetrasodium (2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate
    CAS Number
    PubChem CID
    DrugBank
    ChemSpider
    UNII
    KEGG
    CompTox Dashboard (EPA)
    ECHA InfoCard 100.004.558
    Chemical and physical data
    Formula C11H8Na4O8P2
    Molar mass 422.084 g·mol−1
    3D model (JSmol)
    • CC1=C(C2=CC=CC=C2C(=C1)OP(=O)([O-])[O-])OP(=O)([O-])[O-].[Na+].[Na+].[Na+].[Na+]
    • InChI=1S/C11H12O8P2.4Na/c1-7-6-10(18-20(12,13)14)8-4-2-3-5-9(8)11(7)19-21(15,16)17;;;;/h2-6H,1H3,(H2,12,13,14)(H2,15,16,17);;;;/q;4*+1/p-4 ☒N
    • Key:GZBACHSOZNEZOG-UHFFFAOYSA-J ☒N
     ☒NcheckY (what is this?)  (verify)

    Kappadione is a vitamin K derivative used for the treatment of side effects of vitamin K antagonists such as warfarin, prophylaxis and treatment of vitamin K deficiency bleeding, and hypoprothrombinemia due to various causes. It was manufactured by Eli Lilly and Company. Chemically, it is menadiol sodium diphosphate. It was approved by the US Food and Drug Administration prior to 1982 and marketed by Lilly. It has since been discontinued and is not available in North America.



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