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Antibiotic
Kidamycin
Другие языки:

    Kidamycin

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    Kidamycin
    Kidamycin.svg
    Names
    Other names
    Rubiflavin B
    Identifiers
    3D model (JSmol)
    ChEMBL
    ChemSpider
    PubChem CID
    • InChI=1S/C39H48N2O9/c1-11-17(2)26-15-25(42)29-18(3)12-23-31(37(29)50-26)36(46)32-30(35(23)45)21(27-14-24(40(7)8)33(43)19(4)48-27)13-22(34(32)44)28-16-39(6,41(9)10)38(47)20(5)49-28/h11-13,15,19-20,24,27-28,33,38,43-44,47H,14,16H2,1-10H3/b17-11+
      Key: MFTJRTUKCOVIMD-GZTJUZNOSA-N
    • C/C=C(\C)/C1=CC(=O)C2=C(O1)C3=C(C=C2C)C(=O)C4=C(C3=O)C(=C(C=C4C5CC(C(C(O5)C)O)N(C)C)C6CC(C(C(O6)C)O)(C)N(C)C)
    Properties
    C39H48N2O9
    Molar mass 688.818 g·mol−1
    Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

    Kidamycin is an anthracycline antibiotic with anticancer activity. It was first synthesized from a strain of streptomyces bacteria isolated from a soil sample. In clinical trials, Kindamycin showed high effect against gram positive bacteria as well as multiple cancer models including Ehrlich ascites carcinoma, Sarcoma 180, NF-sarcoma, and Yoshida sarcoma.



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