Kopexil

Kopexil

Names
IUPAC names 2,3-Dihydro-3-hydroxy-2-imino-4-pyrimidinamine 2,4-Diaminopyrimidine 3-N-oxide
Other names Aminexil
Identifiers
CAS Number	113275-13-1 Y 74638-76-9 (pyridine oxide tautomer) Y
3D model (JSmol)	Interactive image
ChemSpider	10445922
EC Number	616-121-2
PubChem CID	10197687
UNII	1756681479
InChI InChI=1S/C4H6N4O/c5-3-1-2-7-4(6)8(3)9/h1-2H,5H2,(H2,6,7) Key: SGHQFNHCCOBUKB-UHFFFAOYSA-N InChI=1S/C4H6N4O/c5-3-1-2-7-4(6)8(3)9/h1-2,6,9H,5H2 Key: YTKGAYFHUZTLCI-UHFFFAOYSA-N
SMILES c1cnc([n+](c1N)[O-])N
Properties
Chemical formula	C4H6N4O
Molar mass	126.119 g·mol−1
Appearance	white odorless crystals
Melting point	210 to 218 °C (410 to 424 °F; 483 to 491 K)
Solubility in water	slightly soluble
Hazards
GHS labelling:
Pictograms
Signal word	Warning
Hazard statements	H302
Precautionary statements	P264, P270, P301+P312, P330, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references

Kopexil (INCI name diaminopyrimidine oxide, trade name Aminexil) is a chemical compound similar to minoxidil. Minoxidil was originally used to treat high blood pressure; a side effect was increased body hair. Both compounds have been used for therapy of alopecia. Kopexil is not approved for use as a drug in the United States or in Europe.

Chemical structure

Kopexil is an N-oxide, a group of substances in which the nitrogen atom of a tertiary amine is oxidized. The compound can exist in two tautomeric forms.

Mechanism of action

The exact mechanism of action of kopexil is unknown. There is no proof of therapeutic effect for kopexil against alopecia.