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Lanthanum carbonate

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Lanthanum carbonate
Names
IUPAC name
Lanthanum carbonate
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.008.728
EC Number
  • 209-599-5
PubChem CID
UNII
  • InChI=1S/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6 checkY
    Key: NZPIUJUFIFZSPW-UHFFFAOYSA-H checkY
  • InChI=1/3CH2O3.2La/c3*2-1(3)4;;/h3*(H2,2,3,4);;/q;;;2*+3/p-6
    Key: NZPIUJUFIFZSPW-CYFPFDDLAT
  • [La+3].[La+3].O=C([O-])[O-].[O-]C([O-])=O.[O-]C([O-])=O
Properties
La2(CO3)3
Molar mass 457.838 g/mol
Appearance White powder, hygroscopic
Density 2.6–2.7 g/cm3
Melting point decomposes
negligible
Solubility soluble in acids
Pharmacology
V03AE03 (WHO)
Related compounds
Other anions
Lanthanum(III) oxide
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Lanthanum carbonate, La2(CO3)3, is the salt formed by lanthanum(III) cations and carbonate anions. It is an ore of lanthanum metal (bastnäsite), along with monazite.

Chemistry

Lanthanum carbonate is used as a starting material in lanthanum chemistry, particularly in forming mixed oxides, for example

Medical uses

Lanthanum carbonate is used in medicine as a phosphate binder. As a medication it is sold under the trade name Fosrenol by the pharmaceutical company Shire Pharmaceuticals. Due to its large size (1000 mg tablet is 2.2 cm in diameter), it may be possible to choke on the tablet if it is not chewed. It is prescribed for the treatment of hyperphosphatemia, primarily in patients with chronic kidney disease. It is taken with meals and binds to dietary phosphate, preventing phosphate from being absorbed by the intestine. For cats with hyperphosphatemia it is available under the trade name Renalzin by Bayer Animal Health.

However, when lanthanum carbonate is used for treating hyperphosphatemia, its side effects, namely myalgia, muscular cramping, and peripheral edema, should be clinically monitored.

Other applications

Lanthanum carbonate is also used for the tinting of glass, for water treatment, and as a catalyst for hydrocarbon cracking.

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