Lipoblast

Histopathology of liposarcoma, H&E stain, with the main features:
- Spindle cells with enlarged, hyperchromatic nuclei.
- Apparently univacuolated adipocytes (may look normal).
- Lipoblasts (multivacuolated), but neither necessary nor sufficient for diagnosis of liposarcoma.

A lipoblast is a precursor cell for an adipocyte.

Alternate terms include adipoblast and preadipocyte.

Early stages are almost indistinguishable from fibroblasts.

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  Lipoblasts (white arrow) and lipocytes (black arrow), in a case of lipoblastoma

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  Micrograph showing a lipoblast (left-bottom of image) in a liposarcoma. H&E stain.

Liposarcoma

Lipoblasts are seen in liposarcoma and characteristically have abundant multivacuolated clear cytoplasm and a dark staining (hyperchromatic), indented nucleus.

See also

• Adipogenesis
• Adipose differentiation-related protein
• Lipoblastoma

• List of human cell types derived from the germ layers