List of antiviral drugs
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Antiviral drugs are different from antibiotics. Flu antiviral drugs are different than antiviral drugs used to treat other infectious diseases such as COVID-19. Antiviral drugs prescribed to treat COVID-19 are not approved or authorized to treat flu.
| Antiviral | Use | Manufacturer | Component | Type | Year approved |
|---|---|---|---|---|---|
| Abacavir | HIV | Nucleoside analogue reverse transcriptase inhibitor (NRTI) | 1998 | ||
| Acyclovir (Aciclovir) | Herpes Simplex, chickenpox,varicella zoster virus | guanosine analogue RTI | 1981 | ||
| Adefovir | Hepatitis B | Gilead Sciences | RTI | 2002 (FDA), 2003 (EU) | |
| Amantadine | Influenza | Influenza A virus M2 proton channel antagonist | |||
| Ampligen | Avian Influenza | Immunomodulatory double-stranded RNA | |||
| Amprenavir (Agenerase) | HIV | Protease inhibitor (PI) | |||
| Umifenovir (Arbidol) | Influenza | Hemagglutinin inhibitor | |||
| Atazanavir | HIV | PI | |||
| Atripla (Efavirenz/emtricitabine/tenofovir) | HIV |
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| Baloxavir marboxil (Xofluza) | Influenza A/B | Cap snatching endonuclease inhibitor | 2018 | ||
| Biktarvy (Bictegravir/emtricitabine/tenofovir alafenamide) | HIV |
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| Boceprevir | Hepatitis C genotype 1 | Schering-Plough, then Merck Group | Protease inhibitor |
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| Bulevirtide | Hepatitis D/B | Sodium/bile acid cotransporter inactivator | |||
| Cidofovir | AIDS | Viral DNA Polymerase inhibitor | |||
| Cobicistat (Tybost) | HIV | human CYP3A protein inhibitor | |||
| Combivir (Lamivudine/Zidovudine) | HIV | ||||
| Daclatasvir (Daklinza) | Hepatitis C | NS5A inhibitor | |||
| Darunavir | HIV | antiretroviral | HIV PI | ||
| Delavirdine | HIV | antiretroviral | NNRTI | ||
| Descovy (Emtricitabine/tenofovir alafenamide) | Hepatitis B |
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| Didanosine | HIV | Adenosine analogue RTI | |||
| Docosanol | Herpes Simplex | Entry inhibitor | |||
| Dolutegravir | HIV | Integrase inhibitor | |||
| Doravirine (Pifeltro) | HIV | NNRTI | |||
| Edoxudine | Herpes Simplex | Thymidine analogue inhibitor | |||
| Efavirenz | HIV | Mylan | NNRTI | 1998 | |
| Elvitegravir | HIV | Gilead Sciences | Integrase inhibitor |
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| Emtricitabine | HIV | Gilead Sciences | NRTI | 2003 | |
| Enfuvirtide | HIV | Entry inhibitor | 2003 | ||
| Ensitrelvir | COVID-19 | Shionogi | 3C-like protease inhibitor | ||
| Entecavir | HIV | NRTI | 2005 | ||
| Etravirine (Intelence) | HIV | NNRTI | 2008 | ||
| Famciclovir | Herpes Zoster | Guanosine analogue | 1994 | ||
| Fomivirsen | AIDS | Anti-sense oligonucleotide | Anti-sense |
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| Fosamprenavir | HIV | ViiV Healthcare | Amprenavir pro-drug | 2003 (FDA), 2004 (EMA) | |
| Foscarnet | Herpes | Pyrophosphate analogue DNA polymerase inhibitor | 1991 | ||
| Ganciclovir (Cytovene) | Cytomegalovirus (CMV) | Competitive nucleoside analogue dGTP inhibitor | 1988 | ||
| Ibacitabine | Herpes labialis | ||||
| Ibalizumab (Trogarzo) | HIV | Entry inhibitor | 2018 | ||
| Idoxuridine | Herpes | dU analogue inhibitor | 1962 | ||
| Imiquimod | Genital wart, Basal cell carcinoma, Actinic keratosis | Opioid growth factor receptor (OGFr) agonist | 1997 | ||
| Inosine pranobex | Herpes Simplex | Thymus hormone immunostimulant | |||
| Indinavir | HIV | PI | 1996 | ||
| Lamivudine | HIV | cytidine analogue RTI | |||
| Letermovir (Prevymis) | Cytomegalovirus (CMV) | ||||
| Lopinavir | HIV | ||||
| Loviride | HIV | ||||
| Maraviroc | HIV | entry inhibitor | |||
| Methisazone | Smallpox | ||||
| Moroxydine | Influenza | ||||
| Nelfinavir | HIV | ||||
| Nirmatrelvir/ritonavir (Paxlovid) | COVID-19 | Pfizer | 3C-like protease inhibitor (Nirmatrelvir) / inhibition of metabolism of nirmatrelvir (ritonavir) | ||
| Nevirapine | HIV | non-nucleoside reverse transcriptase inhibitor | |||
| Nitazoxanide | Broad-spectrum antiviral | thiazolide | |||
| Norvir | HIV | ||||
| Oseltamivir (Tamiflu) | Influenza | neuraminidase inhibitor | |||
| Penciclovir | Herpes | ||||
| Peramivir | Influenza | ||||
| Penciclovir | Herpes | ||||
| Peramivir (Rapivab) | Influenza | ||||
| Pleconaril | Picornavirus | Schering-Plough | |||
| Podophyllotoxin | Genital wart | ||||
| Raltegravir | HIV | Integrase inhibitor | |||
| Remdesivir | COVID-19 | viral RNA polymerase inhibitor | |||
| Ribavirin | Hepatitis C | nucleoside analogue reverse transcriptase inhibitor | |||
| Rilpivirine (Edurant) | HIV | ||||
| Rilpivirine | HIV | ||||
| Rimantadine | Influenza A | M2 proton channel antagonist | |||
| Ritonavir | HIV | HIV-1 protease inhibitor | |||
| Saquinavir | HIV | ||||
| Simeprevir (Olysio) | Hepatitis C | ||||
| Sofosbuvir | Hepatitis C | nucleoside analogue reverse transcriptase inhibitor | |||
| Stavudine | HIV | ||||
| Taribavirin (Viramidine) | Hepatitis Syndromes in which Ribavirin is active | ||||
| Telaprevir | Hepatitis C | ||||
| Telbivudine (Tyzeka) | Hepatitis B | ||||
| Tenofovir alafenamide | Hepatitis B | ||||
| Tenofovir disoproxil | Hepatitis B, HIV | ||||
| Tipranavir | HIV | ||||
| Trifluridine | Eyes related Herpes | ||||
| Trizivir | HIV | ||||
| Tromantadine | Herpes Simplex | ||||
| Truvada | HIV | ||||
| Umifenovir | Influenza | ||||
| Valaciclovir (Valtrex) | Herpes Simplex/Zoster | ||||
| Valganciclovir (Valcyte) | Cytomegalovirus (CMV) | ||||
| Vicriviroc | HIV-1 | Schering-Plough | pyrimidine CCR5 entry inhibitor | ||
| Vidarabine | Herpes Simplex, Varicella Zoster | ||||
| Zalcitabine | HIV | ||||
| Zanamivir (Relenza) | Influenza A, Influenza B | ||||
| Zidovudine | HIV | Antiretroviral |