LY-307,452

LY-307,452

Identifiers
IUPAC name (2S,4S)-2-amino-4-(4,4-diphenylbut-1-yl)pentan-1,5-dioic acid
CAS Number	174393-13-6
PubChem CID	6324634
IUPHAR/BPS	3350
ChemSpider	4884363 N
Chemical and physical data
Formula	C21H25NO4
Molar mass	355.434 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1=CC=C(C=C1)C(CCC[C@@H](C[C@@H](C(=O)O)N)C(=O)O)C2=CC=CC=C2
InChI InChI=1S/C21H25NO4/c22-19(21(25)26)14-17(20(23)24)12-7-13-18(15-8-3-1-4-9-15)16-10-5-2-6-11-16/h1-6,8-11,17-19H,7,12-14,22H2,(H,23,24)(H,25,26)/t17-,19-/m0/s1 N Key:DWLOVDOPFJPWNE-HKUYNNGSSA-N N
NY (what is this?)  (verify)

LY-307,452 is a drug used in neuroscience research, which was among the first compounds found that acts as a selective antagonist for the group II metabotropic glutamate receptors (mGluR_2/3), and was useful in early studies of this receptor family, although it has largely been replaced by newer drugs such as LY-341,495. Its molecular formula is C₂₁H₂₅NO₄