Manchester score

Manchester score is an indicator of prognosis in small cell lung cancer. It is calculated from a number of physical and biochemical markers.

A patient with small cell lung cancer scores one point for each of the following:-

• Serum lactate dehydrogenase exceeds the upper limit of the reference range.
• Serum sodium concentration less than 132 mmol/L.
• Serum alkaline phosphatase over one-and-a-half times the upper limit of the reference range.
• Serum bicarbonate less than 24.
• Karnofsky performance status less than 60.
• Extensive stage disease.

Prognosis