Minaprine
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| Clinical data | |
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| AHFS/Drugs.com | International Drug Names |
| Routes of administration |
Oral |
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| Pharmacokinetic data | |
| Elimination half-life | 2-2.5 hours |
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| CompTox Dashboard (EPA) | |
| ECHA InfoCard | 100.043.012 |
| Chemical and physical data | |
| Formula | C17H22N4O |
| Molar mass | 298.390 g·mol−1 |
| 3D model (JSmol) | |
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Minaprine (INN, USAN, BAN) (brand names Brantur, Cantor) is a monoamine oxidase inhibitor antidepressant drug that was used in France for the treatment of depression until it was withdrawn from the market in 1996 because it caused convulsions.
A study found that it acts as a reversible inhibitor of MAO-A (RIMA) in rats. In a study it has also been found to weakly inhibit acetylcholinesterase in rat brain (striatum) homogenates.
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Phenethylamines (dopamine, epinephrine, norepinephrine) |
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Tryptamines (serotonin, melatonin) |
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