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Abandoned drugs
Mitozolomide
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    Mitozolomide

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    Mitozolomide
    Mitozolomide.svg
    Clinical data
    ATC code
    • none
    Identifiers
    • 3-(2-chloroethyl)-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    CompTox Dashboard (EPA)
    ECHA InfoCard 100.079.921
    Chemical and physical data
    Formula C7H7ClN6O2
    Molar mass 242.62 g·mol−1
    3D model (JSmol)
    • NC(=O)c1ncn2C(=O)N(CCCl)\N=N/c12
    • InChI=1S/C7H7ClN6O2/c8-1-2-14-7(16)13-3-10-4(5(9)15)6(13)11-12-14/h3H,1-2H2,(H2,9,15) ☒N
    • Key:QXYYYPFGTSJXNS-UHFFFAOYSA-N ☒N
     ☒NcheckY (what is this?)  (verify)

    Mitozolomide (INN) is an antineoplastic. It is an imidazotetrazine derivative.

    Development of mitozolomide was discontinued during Phase II clinical trials after it was found to cause severe and unpredictable bone marrow suppression.Temozolomide, which has been in clinical use since 1999, is a less toxic analogue of mitozolomide.


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