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Abandoned drugs
Monalazone
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    Monalazone

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    Monalazone
    Monalazone.svg
    Clinical data
    Trade names Naclobenz-Natrium, Spergisin, Speton
    Other names p-(Chlorosulfamoyl)benzoic acid
    Routes of
    administration    		 Vaginal
    Drug class Disinfectant
    ATC code
    • None
    Identifiers
    • 4-(chlorosulfamoyl)benzoic acid
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    ChEMBL
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C7H6ClNO4S
    Molar mass 235.64 g·mol−1
    3D model (JSmol)
    • C1=CC(=CC=C1C(=O)O)S(=O)(=O)NCl
    • InChI=1S/C7H6ClNO4S/c8-9-14(12,13)6-3-1-5(2-4-6)7(10)11/h1-4,9H,(H,10,11)
    • Key:WGHSWNHOFPGMKJ-UHFFFAOYSA-N

    Monalazone, used as monalazone disodium (INN; the disodium salt) and sold under the brand names Naclobenz-Natrium, Spergisin, and Speton, is a vaginal disinfectant or antiseptic and spermicidal contraceptive. It is a sulfonylbenzoic acid derivative and is closely related structurally to halazone. The compound was synthesized in 1937. A vaginal tablet combination of 0.125 mg estradiol benzoate and 10 mg monalazone was previously marketed under the brand name Malun 25.



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