N-Methyl-PPPA

N-Methyl-PPPA

Clinical data
Other names	Detrifluoromethylfluoxetine
ATC code	None
Identifiers
IUPAC name N-Methyl-3-phenoxy-3-phenyl-1-propanamine
ChemSpider	16340904
Chemical and physical data
Formula	C16H19NO
Molar mass	241.334 g·mol−1
3D model (JSmol)	Interactive image
SMILES CNCCC(Oc1ccccc1)c2ccccc2
InChI InChI=1S/C16H19NO/c1-17-13-12-16(14-8-4-2-5-9-14)18-15-10-6-3-7-11-15/h2-11,16-17H,12-13H2,1H3 Key:DMOUAPYFRKLFHO-UHFFFAOYSA-N

N-Methyl-PPPA, or N-methyl-3-phenoxy-3-phenylpropan-1-amine, is a serotonin-norepinephrine reuptake inhibitor (SNRI) which was developed by Eli Lilly from diphenhydramine in the early 1970s while in search of new antidepressants, but was never marketed. It is closely related structurally to fluoxetine, atomoxetine, and nisoxetine.

See also

• 3-Phenoxy-3-phenylpropan-1-amine (PPPA)
• Development and discovery of SSRI drugs
• Aryloxypropanamine scaffold