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Anticonvulsant
Nafimidone
Другие языки:

Nafimidone

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Nafimidone
Nafimidone-2D-skeletal.png
Nafimidone-from-xtal-2005-CM-3D-balls.png
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
Chemical and physical data
Formula C15H12N2O
Molar mass 236.274 g·mol−1
3D model (JSmol)
  • C1=CC=C2C=C(C=CC2=C1)C(=O)CN3C=CN=C3
  • InChI=1S/C15H12N2O/c18-15(10-17-8-7-16-11-17)14-6-5-12-3-1-2-4-13(12)9-14/h1-9,11H,10H2 ☒N
  • Key:ITPVLJQRUQVNSD-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Nafimidone is an anticonvulsant drug of the imidazole class. It contains a naphthyl group. It seems to have been discovered by accident during a search for antifungal agents.

Synthesis

Nafimidone synthesis:

Its synthesis is straightforward displacement of imidazole of the activated chlorine atom of chloro-methyl-β-naphthylketone.


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