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Antipsychotic
Neboglamine
Другие языки:

    Neboglamine

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    Neboglamine
    Neboglamine.svg
    Clinical data
    Other names Nebostinel; N-(4,4-Dimethylcyclohexyl)-L-α-glutamine
    ATC code
    • None
    Identifiers
    • (4S)-4-Amino-5-[(4,4-dimethylcyclohexyl)amino]-5-oxopentanoic acid
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    ECHA InfoCard 100.162.081
    Chemical and physical data
    Formula C13H24N2O3
    Molar mass 256.346 g·mol−1
    3D model (JSmol)
    • CC1(CCC(CC1)NC(=O)C(CCC(=O)O)N)C
    • InChI=1S/C13H24N2O3/c1-13(2)7-5-9(6-8-13)15-12(18)10(14)3-4-11(16)17/h9-10H,3-8,14H2,1-2H3,(H,15,18)(H,16,17)/t10-/m0/s1
    • Key:VCRGLZYPNNAVRP-JTQLQIEISA-N

    Neboglamine (INN) (developmental code names CR-2249, XY-2401), formerly known as nebostinel, is a positive allosteric modulator of the glycine site of the NMDA receptor which is under investigation for Rottapharm for the treatment of schizophrenia and cocaine dependence. It shows cognition- and memory-enhancing effects in animal models. As of June 2015, it is in phase II clinical trials for both schizophrenia and cocaine abuse.

    See also

    External links



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