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Abandoned drugs
Nonabine
Другие языки:

Nonabine

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Nonabine
Nonabine.png
Clinical data
ATC code
  • none
Legal status
Legal status
  • Not approved for any medical use
Identifiers
  • 7-(1,2-Dimethylheptyl)-2,2-dimethyl-4-(4-pyridinyl)-2H-1-benzopyran-5-ol
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
Formula C25H33NO2
Molar mass 379.544 g·mol−1
3D model (JSmol)
  • CCCCCC(C)C(C)c1cc(c2c(c1)OC(C=C2c3ccncc3)(C)C)O
  • InChI=1S/C25H33NO2/c1-6-7-8-9-17(2)18(3)20-14-22(27)24-21(19-10-12-26-13-11-19)16-25(4,5)28-23(24)15-20/h10-18,27H,6-9H2,1-5H3 ☒N
  • Key:YHUDSHIRWOVVCV-UHFFFAOYSA-N ☒N
 ☒NcheckY (what is this?)  (verify)

Nonabine (BRL-4664) is an experimental drug which is a synthetic THC analog. It was studied in the 1980s for the prevention of nausea and vomiting associated with cancer chemotherapy but was never marketed. It has strong antiemetic effects equivalent to those of chlorpromazine, and also produces some mild sedative effects, along with dry mouth and EEG changes typical of cannabinoid agonists, but with minimal changes in mood or perception, suggesting the abuse potential is likely to be low.


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