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Oxomemazine/guaifenesin
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Oxomemazine/guaifenesin

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Oxomemazine/guaifenesin
Oxomemazine and guaifenesin.svg
Combination of
Oxomemazine H1 receptor antagonist
(antihistamine)
Guaifenesin expectorant
Clinical data
Trade names Toplexil and others
Routes of
administration
Oral
ATC code
  • none
Identifiers
CAS Number

Oxomemazine/guaifenesin is a sedative antihistamine plus expectorant. It is a combination of oxomemazine and guaifenesin.

It is sold under a variety of brand names including Toplexil by Aventis. It is sold over the counter in France, Morocco, Egypt, Algeria, South Korea and the UAE. The oxomemazine ingredient (antihistamine) is not approved by the U.S. Food and Drug Administration (FDA), either for over the counter or prescription use. It is sold in France as cough syrup. French travelers also use it as a sleeping aid for long flights.


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