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Abandoned drugs
Perafensine
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    Perafensine

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    Perafensine
    Skeletal formula of perafensine
    Clinical data
    ATC code
    • None
    Legal status
    Legal status
    • Abandoned
    Identifiers
    • 1-phenyl-3-(1-piperazinyl)isoquinoline
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C19H19N3
    Molar mass 289.382 g·mol−1
    3D model (JSmol)
    • c1ccc(cc1)c2c3ccccc3cc(n2)N4CCNCC4
    • InChI=1S/C19H19N3/c1-2-6-15(7-3-1)19-17-9-5-4-8-16(17)14-18(21-19)22-12-10-20-11-13-22/h1-9,14,20H,10-13H2
    • Key:BHHDTFRLKOTSKW-UHFFFAOYSA-N

    Perafensine (INN) (code name HR-459) is a drug which was investigated as an antidepressant but was never marketed. It has been reported to antagonize the effects of reserpine and to inhibit the reuptake of norepinephrine (norepinephrine reuptake inhibitor); whether it also affects the reuptake of serotonin or dopamine is unclear.

    See also


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