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Rodenticide
Pyrinuron
Другие языки:

Pyrinuron

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Pyrinuron
Pyrinuron Structure.svg
Names
Preferred IUPAC name
N-(4-Nitrophenyl)-N′-[(pyridin-3-yl)methyl]urea
Other names
Pyriminil
Vacor
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.053.279
PubChem CID
UNII
  • InChI=1S/C13H12N4O3/c18-13(15-9-10-2-1-7-14-8-10)16-11-3-5-12(6-4-11)17(19)20/h1-8H,9H2,(H2,15,16,18) checkY
    Key: CLKZWXHKFXZIMA-UHFFFAOYSA-N checkY
  • InChI=1/C13H12N4O3/c18-13(15-9-10-2-1-7-14-8-10)16-11-3-5-12(6-4-11)17(19)20/h1-8H,9H2,(H2,15,16,18)
    Key: CLKZWXHKFXZIMA-UHFFFAOYAA
  • [O-][N+](=O)c1ccc(cc1)NC(=O)NCc2cccnc2
Properties
C13H12N4O3
Molar mass 272.264 g·mol−1
Hazards
Occupational safety and health (OHS/OSH):
Main hazards
 Toxic
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Pyrinuron (Pyriminil, Vacor) is a chemical compound formerly used as a rodenticide. Commercial distribution was voluntarily suspended in 1979 and it is not approved by the Environmental Protection Agency for use in the United States. If it is ingested by humans in high doses, it may selectively destroy insulin-producing beta cells in the pancreas causing type 1 diabetes. The neurodegeneration associated with Vacor is caused by its conversion to Vacor-mononucleotide (VMN) by NAMPT and VMN's subsequent activation of the NADase SARM1.



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