Queen bee acid

Queen bee acid

Names
Preferred IUPAC name (2E)-10-Hydroxydec-2-enoic acid
Other names 10-Hydroxy-2-decenoic acid Royal Jelly acid
Identifiers
CAS Number	14113-05-4 Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:78668
ChemSpider	4472163
MeSH	C055543
PubChem CID	5312738
UNII	76B519G7TJ Y
CompTox Dashboard (EPA)	DTXSID50997870
InChI InChI=1S/C10H18O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h6,8,11H,1-5,7,9H2,(H,12,13)/b8-6+ Key: QHBZHVUGQROELI-SOFGYWHQSA-N InChI=1/C10H18O3/c11-9-7-5-3-1-2-4-6-8-10(12)13/h6,8,11H,1-5,7,9H2,(H,12,13)/b8-6+ Key: QHBZHVUGQROELI-SOFGYWHQBH
SMILES C(CCC/C=C/C(=O)O)CCCO
Properties
Chemical formula	C10H18O3
Molar mass	186.251 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Infobox references

The queen bee acid (10-hydroxy-2-decenoic acid) or 10-HDA is a bio-active compound found in royal jelly.

Royal jelly acid is being investigated for its pharmacological activities. Reports indicate that it promotes neurogenesis of neural stem/progenitor cells (cells capable of differentiating into neurons, astrocytes, or oligodendrocytes) in vitro and could provide an effective method to treat and prevent neurological disorders.

In addition, royal jelly acid has been reported to have anti-tumor, anti-biotic, immunomodulatory, estrogenic, neurogenic, and innate immune response modulating activities.

In the United States, the Food and Drug Administration has taken legal action against companies that have used unfounded claims of health benefits to market royal jelly products.

See also

• 10-Hydroxydecanoic acid
• 2-Decenedioic acid

• 10-Hydroxy-2-decenoic Acid, a Major Fatty Acid from Royal Jelly, Inhibits VEGF-induced Angiogenesis in Human Umbilical Vein Endothelial Cells

9. Royal Jelly Uses, Side Effects & Warnings https://www.drugs.com/mtm/royal-jelly.html Medically reviewed by Drugs.com on Sep 29, 2020. Written by Cerner Multum.