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Antiprotozoal agents
Quinfamide
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    Quinfamide

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    Quinfamide
    Quinfamide.svg
    Clinical data
    Routes of
    administration    		 Oral
    ATC code
    • None
    Identifiers
    • [1-(2,2-dichloroacetyl)-3,4-dihydro-2H-quinolin-6-yl] furan-2-carboxylate
    CAS Number
    PubChem CID
    ChemSpider
    UNII
    CompTox Dashboard (EPA)
    ECHA InfoCard 100.057.690
    Chemical and physical data
    Formula C16H13Cl2NO4
    Molar mass 354.18 g·mol−1
    3D model (JSmol)
    • C1CC2=C(C=CC(=C2)OC(=O)C3=CC=CO3)N(C1)C(=O)C(Cl)Cl
    • InChI=1S/C16H13Cl2NO4/c17-14(18)15(20)19-7-1-3-10-9-11(5-6-12(10)19)23-16(21)13-4-2-8-22-13/h2,4-6,8-9,14H,1,3,7H2 ☒N
    • Key:SBJGFIXQRZOVTO-UHFFFAOYSA-N ☒N
     ☒NcheckY (what is this?)  (verify)

    Quinfamide is a drug that has anti-parasitic properties.

    Synthesis

    Quinfamide is one of a relatively small family of antiamoebic compounds containing a dichloroacetamide function.

    Quinfamide synthesis:

    The synthesis begins by amidation of 6-hydroxytetrahydroquinoline with dichloroacetyl chloride. The sequence is completed by acylation with 2-furoyl chloride.


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