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Abandoned drugs
Ro-44-3888
Другие языки:

    Ro-44-3888

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    Ro-44-3888
    Ro 44-3888.svg
    Identifiers
    PubChem CID
    ChemSpider
    ChEMBL
    Chemical and physical data
    Formula C18H24N4O5
    Molar mass 376.413 g·mol−1
    3D model (JSmol)
    • C[C@@H](C(=O)N1CCC(CC1)OCC(=O)O)NC(=O)C2=CC=C(C=C2)C(=N)N
    • InChI=1S/C18H24N4O5/c1-11(21-17(25)13-4-2-12(3-5-13)16(19)20)18(26)22-8-6-14(7-9-22)27-10-15(23)24/h2-5,11,14H,6-10H2,1H3,(H3,19,20)(H,21,25)(H,23,24)/t11-/m0/s1
    • Key:BHOGTSLQMNCJHA-NSHDSACASA-N

    Ro 44-3888 is a non-peptidic, selective and reversible glycoprotein IIb/IIIa inhibitor. It is the active metabolite of sibrafiban. It was being investigated as a treatment for heart conditions, including myocardial infarctions. The development of Ro 44-3888 and sibrafiban was discontinued in 1999 following unfavorable Phase III efficacy data.

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