Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Antihypertensive
Rostafuroxin
Другие языки:

Rostafuroxin

Подписчиков: 0, рейтинг: 0
Rostafuroxin
Rostafuroxin.svg
Names
IUPAC name
21,23-Epoxy-24-nor-5β-chola-20,22-diene-3β,14β,17-triol
Systematic IUPAC name
(1S,3aS,3bR,5aR,7S,9aS,9bS,11aS)-1-(Furan-3-yl)-9a,11a-dimethylhexadecahydro-3aH-cyclopenta[a]phenanthrene-1,3a,7-triol
Identifiers
3D model (JSmol)
PubChem CID
UNII
  • C[C@]12CC[C@@H](C[C@H]1CC[C@@H]3[C@@H]2CC[C@]4([C@@]3(CC[C@@]4(C5=COC=C5)O)O)C)O
Properties
C23H34O4
Molar mass 374.521 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Rostafuroxin is a digitoxigenin analog that has been shown to lower blood pressure in an animal model of hypertension. It modulates the effects of the enzyme Na+/K+-ATPase, which maintains sodium and potassium ion gradients across plasma membranes. Rostafuroxin is being studied in clinical trials for the treatment of essential hypertension.


Новое сообщение