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Medical imaging
RTI-32
Другие языки:

    RTI-32

    Подписчиков: 0, рейтинг: 0
    RTI-32
    Phenyltropane 11f.svg
    Identifiers
    • Methyl (1R,2S,3S,5S)-8-methyl-3-(4-methylphenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate
    CAS Number
    PubChem CID
    ChemSpider
    ChEMBL
    CompTox Dashboard (EPA)
    Chemical and physical data
    Formula C17H23NO2
    Molar mass 273.376 g·mol−1
    3D model (JSmol)
    • CC1=CC=C(C=C1)[C@H]2C[C@@H]3CC[C@H]([C@H]2C(=O)OC)N3C
    • InChI=1S/C17H23NO2/c1-11-4-6-12(7-5-11)14-10-13-8-9-15(18(13)2)16(14)17(19)20-3/h4-7,13-16H,8-10H2,1-3H3/t13-,14+,15+,16-/m0/s1
    • Key:MMKZDDDDODERSJ-JJXSEGSLSA-N
      (verify)

    (–)-2β-Carbomethoxy-3β-(4-tolyl)tropane (RTI-4229-32, tolpane) is a phenyltropane-based cocaine analogue that has similar properties in vitro to related drugs such as RTI-31.

    Comparison of Data
    Compound DAT DA NET NA SERT 5HT ED50
    Troparil 23 49.8 550 37.2 178 173 0.34
    RTI-32 1.7 7.02 36 8.42 23 19.4 0.31
    RTI-31 1.1 3.68 22 5.86 4.0 5.0 0.13
    3'4'-xylyl 0.43 unknown 44 unknown 2.42 unknown

    See also


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