Мы используем файлы cookie.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Продолжая использовать сайт, вы даете свое согласие на работу с этими файлами.
Rugulosin
Подписчиков: 0, рейтинг: 0
Names | |
---|---|
IUPAC name
8,10,14,23,25,28-hexahydroxy-6,21-dimethyloctacyclo[14.11.1.02,11.02,15.04,9.013,17.017,26.019,24]octacosa-4(9),5,7,10,19(24),20,22,25-octaene-3,12,18,27-tetrone
| |
Other names
NSC 160880
NSC 249990 Rugulosin A | |
Identifiers | |
|
|
3D model (JSmol)
|
|
ChEBI | |
ChemSpider | |
KEGG | |
PubChem CID
|
|
UNII | |
CompTox Dashboard (EPA)
|
|
| |
| |
Properties | |
C30H22O10 | |
Molar mass | 542.496 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|
Rugulosin is an anthraquinoid mycotoxin with the molecular formula C30H22O10 which is produced by Penicillium species. Rugulosin is hepatotoxic and is cancerogenic.
Further reading
- Eckardt, Christiane (1981). Mykotoxine in Lebensmitteln (in German). Fischer. p. 23. ISBN 978-3-437-10650-7.
- Studies in Natural Products Chemistry. Elsevier. 24 April 2015. ISBN 978-0-444-63469-6.
- Steyn, Pieter (2 December 2012). The Biosynthesis of Mycotoxins: A study in secondary Metabolism. Elsevier. p. 375. ISBN 978-0-323-14993-8.
- Pirttilä, Anna Maria; Frank, A. Carolin (11 July 2011). Endophytes of Forest Trees: Biology and Applications. Springer Science & Business Media. p. 244. ISBN 978-94-007-1599-8.
- Nicolaou, K. C.; Lim, Yee Hwee; Piper, Jared L.; Papageorgiou, Charles D. (1 April 2007). "Total Syntheses of 2,2'-epi-Cytoskyrin A, Rugulosin, and the Alleged Structure of Rugulin". Journal of the American Chemical Society. 129 (13): 4001–4013. doi:10.1021/ja0685708. ISSN 0002-7863. PMID 17355133.
- Mondal, Amit; Singh, Shailesh Kumar; Manna, Tanaya; Husain, Syed Masood (17 March 2020). "Chemoenzymatic, biomimetic total synthesis of (−)-rugulosin B, C and rugulin analogues and their biosynthetic implications". Chemical Communications. 56 (22): 3337–3340. doi:10.1039/D0CC00406E. ISSN 1364-548X. PMID 32090214. S2CID 211262650.
- Nicolaou, K. C.; Lim, Yee Hwee; Papageorgiou, Charles D.; Piper, Jared L. (2005). "Total Synthesis of (+)-Rugulosin and (+)-2,2′-epi-Cytoskyrin A through Cascade Reactions". Angewandte Chemie International Edition. 44 (48): 7917–7921. doi:10.1002/anie.200503678. ISSN 1521-3773. PMID 16342134.
- Sumarah, Mark W.; Miller, J. David; Adams, Gregory W. (1 September 2005). "Measurement of a rugulosin-producing endophyte in white spruce seedlings". Mycologia. 97 (4): 770–776. doi:10.1080/15572536.2006.11832768. ISSN 0027-5514. PMID 16457346. S2CID 218590435.