SCHEMBL19952957

SCHEMBL19952957

Identifiers
IUPAC name 4-[3-(4-cyclopentyloxyphenyl)-1,2,4-oxadiazol-5-yl]phenol
PubChem CID	137279743
Chemical and physical data
Formula	C19H18N2O3
Molar mass	322.364 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CCC(C1)OC2=CC=C(C=C2)C3=NOC(=N3)C4=CC=C(C=C4)O
InChI InChI=1S/C19H18N2O3/c22-15-9-5-14(6-10-15)19-20-18(21-24-19)13-7-11-17(12-8-13)23-16-3-1-2-4-16/h5-12,16,22H,1-4H2 Key:LTWUHRPUKBTFBZ-UHFFFAOYSA-N

SCHEMBL19952957 is an oxadiazole based antibiotic, originally developed in 2014 as a potential treatment for infections with methicillin-resistant Staphylococcus aureus (MRSA) and other antibiotic resistant bacteria. Subsequently, it has been found to be useful against Clostridium difficile as it not only kills active bacteria, but also inhibits the germination of the dormant spores which can otherwise often lead to persistent infections that repeatedly recur upon cessation of antibiotic treatment. While it is still only being researched in animals at this stage, this dual action is a significant advance over existing antibiotics, and it is likely that drugs from this class may be developed as new medications for the treatment of antibiotic resistant infections in humans.

See also

• Cadazolid
• Fidaxomicin
• Ridinilazole
• Surotomycin